- Similar to LC/MS/MS
- Added degree of selectivity
- Trace analysis in:
- Environmental samples (i.e. soil, water, sediment)
- Pharmaceutical analyses (i.e. active ingredient or impurity analyses)
- Biological samples (i.e. crops, livestock tissues, milk, eggs, blood, urine)
- Structure confirmation analyses
- Direct injection MS/MS (no LC separation)
- Analysis of compounds lacking UV chromophores
- Updating existing methodology for higher specificity or sensitivity